The lysosome is a small membrane bound organelle that can be found in most animal cells. It was once thought that these little sacs were like recycling centers that could take up cellular waste ...

Scientists in the lab of chemical engineer Monther Abu-Remaileh are uncovering the cellular functions that go awry in ...

Lysosomes are basically the cell’s trash and recycling centers. “I don’t think it’s possible for lysosomes to all pop at the same time,” Omsland said.

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes ...

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

The team discovered that peroxidation of lysosomes plays a key role in the execution of ferroptosis-mediated cell death. Additionally, they found that lysosomal lipid peroxidation causes the membrane ...

The researchers found that cells usually take around an hour to repair damaged lysosomes, but this healing requires up to 11 hours in cells lacking PI42KA. “It looks like quite a significant pathway, ...

Think back to that basic biology class you took in high school. You probably learned about organelles, those little "organs" ...

There are about 50 to 60 enzymes inside the lysosomes that digest worn-out cellular parts as well as waste from outside the cell. The lysosome also recycles this waste -- proteins, nucleic acid ...

Ferroptosis, a form of programmed cell death mediated by iron, has been a focus for its potential in cancer therapies. Now, researchers have discovered that lysosomal lipid peroxidation plays a ...