I n a stunning breakthrough, scientists have successfully engineered a living mouse using a gene that predates animal life by hundreds of millions of years. This study, published in Nature ...

・Key experiment: Introduction of the Sox2 gene from choanoflagellates to replace the Sox2 gene in mouse cells. ・Key outcome: The cells were successfully reprogrammed into stem cells ...

Scientists at the Dallas-based Colossal Biosciences have taken a small step towards their goal of bringing back the woolly mammoth: they've created the woolly mouse ...

Colossal Biosciences has focused on identifying key traits of extinct animals by studying ancient DNA, with a goal to genetically "engineer them into living animals," said CEO Ben Lamm.

Woolly mammoths once roamed icy landscapes before going extinct around 4,000 years ago. Now, US biotech firm Colossal ...

The Colossal scientists reviewed DNA databases of mouse genes to identify genes related to hair texture and fat metabolism.

Figure 1: Imaging of amyloid-β deposits in the live mouse. Figure 3: In vivo imaging of amyloid-β deposits in 20-month-old homozygous PDAPP mice. Immunostaining with biotinylated or ...

Dallas-based Colossal is one step closer to bringing back the woolly mammoth.

Colossal Biosciences announced it has genetically engineered the Colossal Woolly Mouse, which has a warm coat like the woolly mammoth.