In biomedical research, so-called organs-on-a-chip, also referred to as microphysiological systems, are becoming increasingly ...

Femtosecond source produces precise, stable channels for blood supply in tissue models. The breakthrough, described in ...

Leading the alternative methodology sector are organ-on-a-chip (OOC) models, or microphysiological systems ... Figure 1: A confocal image of MASH liver tissue generated using MPS. Credit: CN Bio.

Miniature organs on a chip could allow us to do scientific studies with great precision, without having to resort to animal testing. The main problem, however, is that artificial tissue needs blood ...

Using an Organ-on-a-chip (OOC) approach, the microarchitecture of liver tissue can be closely reproduced by growing physiologically relevant compilations of primary liver cells (including those ...

Already, this technology has been used to mimic various individual organs into a chip format, including the liver, lung, tumours, and muscles, among others. As the technology advances further ...

Now these organs on chips, also known as microphysiological ... “genius grant,” designed a crude early version of a liver chip in the late 1990s: a flat silicon chip, just a few hundred ...

For instance, Bayer is collaborating with TissUse for a liver and multi-organ-on-a-chip model. Roche is using chips developed by Mimetas to study the effects of inflammatory bowel disease and ...

Additionally, organ-on-chip technology is not just applicable to the liver, lung, and heart; in recent years, much focus has been placed on extending the organ's applications and sites.

In one high-profile deployment, CN Bio's liver-on-chip system was used to ... suggest a growing regulatory openness to organ-on-chip data within drug evaluation processes. Crucially, such FDA ...