Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

During the evolution of linear genomes, it became essential to protect the natural chromosome ends to prevent triggering of the DNA-damage repair machinery and enzymatic attack. Telomeres ...

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have ...

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A ...

The fact that TAg was expressed after DNA replication suggested it was expressed too late to be responsible for driving cells into replicating their DNA. Sunnie Thompson, Ph.D. TAg expression and ...

New model for replication of BKPyV virus, a major cause of kidney transplant failure There are no effective antivirals against BK polyomavirus in transplanted kidneys.

The expectation of the model with single-character indels (M1). Three types of solution are possible: exponential growth when pi>pd, linear growth when pi=pd, exponential decay to a steady-state ...

A new model of DNA flexibility has been developed by Kim López-Güell, a Maths4Life student, together with Dr. Federica Battistini, under the supervision of Dr. Modesto Orozco in the Molecular ...