However, the precise mechanisms by which lens proteins both prevent aggregation and maintain lens transparency are largely unknown. Lanosterol is an amphipathic molecule enriched in the lens.

α-Crystallin is a major lens protein, comprising up to 40% of total lens proteins, where its structural function is to assist in maintaining the proper refractive index in the lens. In addition ...

New research reveals how proteins that are critical for the transparency of the eye lens are properly sorted and localized in membrane bilayers. The study analyzes how interactions between lipid ...

The mechanism behind how proteins that are critical for the transparency of the eye lens are properly sorted and localized in membrane bilayers has been highlighted in new research.

A molecular dance of sorts between two proteins in the eye lens can create either perfect vision or cloudy cataracts. By applying physics and biology to the complexities of vision, scientists ...

By studying protein accumulation in the nematode worm C. elegans Dr Della David and her team found that even when the typical protein quality control mechanisms were disrupted, there were lower levels ...

With the help of such a protein aggregation clock, they hope that scientists and doctors will be able to move one step closer towards helping people age healthily and preventing age-related diseases.