This study provides compelling evidence that kinesin's stepping mechanism is governed by strain-induced conformational changes in its nucleotide-binding pockets. Using pre-steady state kinetics and ...

Using mouse neurons as a model, the scientists showed that APP serves as an attachment point for a molecular motor called kinesin, which transports packets of protein from the main cell body along the ...

With this strategy, Hell’s team fluorescently tagged and tracked a motor protein called kinesin as it performed its signature ... has already harnessed the previous iteration of MINFLUX to visualize ...

Similarly, scientists discovered that motor memory — as indicated ... In our study, we speculated that kinesin was used to deliver molecular materials for “building” dendritic spines.

Our current projects are the following: Structure & function of heterodimeric kinesin motor domains, interactions of microtubules with MAPs, and structural studies on the Giardia cytoskeleton.

Kinesin with vesicle is attached with two "feet" to the cell's microtubule. This is a safe and stable time period. The kinesin untethers its back foot and moves it forward. This is a vulnerable ...