This study provides compelling evidence that kinesin's stepping mechanism is governed by strain-induced conformational changes in its nucleotide-binding pockets. Using pre-steady state kinetics and ...

With this strategy, Hell’s team fluorescently tagged and tracked a motor protein called kinesin as it performed its signature walk down the length of a microtubule. Kinesin is a vital player in ...

This increase in plus-end-directed microtubule movements could be inhibited by an antibody against the plus-end-directed kinesin Eg5, or by a specific Eg5 inhibitor called monastrol, indicating ...

In recent years, similar phenomena have been observed with active micro-units such as bacteria, chemically-activated motile colloids, even microtubule–kinesin bundles (active nematics) Active matter ...