Stem-cell derived organoids provide the perfect mixture of cells to rebuild damaged intestines.

In a recent study, FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells for gut ... "As the organoid's lumen volume decreases, the tissue ...

The use of the heterogeneous and ill-defined 3D cell culture platform Matrigel has facilitated organoid culture with impressive ... and bond formation to study how intestinal stem cell colonies ...

Caption A single human intestinal organoid, or HIO -- a hollow ball of cells grown from human embryonic stem cells and coaxed to become gut-lining cells. Scientists can use it to study basic gut ...

Intestinal organoids ... and reproducibility challenges in organoid systems. In a recently published Science paper, 1 his team described how they developed a biomaterial tissue scaffold that allows ...

Baseline culture conditions are sufficient for the growth of porcine intestinal mucosal organoids. The company believes it has established stem cell organoid cultures from anal skin for the first ...

By comparing young and aged mouse intestinal tissues, the researchers uncovered critical insights into the interplay between these signaling pathways in supporting stem cell maintenance over time.

Organoids are made to model human organs and are promising for research and therapy, but there are limitations in their growth and function. A recent study found that placenta-derived IL1 under ...

began with a genome-wide genetic screen based on CRISPR interference (CRISPRi) that systemically reduces the expression of every single gene in the genome of a pluripotent stem cell (PSC ...

In cystic fibrosis, researchers have used CRISPR HDR-mediated knock-in to correct mutations in the CFTR gene in airway stem cells ... for drug development. Organoid and organ-on-a-chip models ...