suggesting that cationic bovine serum albumin is pathogenic through binding to the anionic glomerular capillary wall and in situ formation of immune complexes, as shown in experimental models.

The pathogenetic links between viral infection and renal disease are often difficult to establish. The criteria for proving causality are complex and include (besides recognition of the clinical ...

The initial renal biopsy of the case presented here revealed immune-complex-mediated tubulointerstitial nephritis. As there was no evidence of systemic disease, drug use, herbal supplement intake ...

The review examined the potential of combining checkpoint blockade therapy within situ vaccination as ... considerable heterogeneity and complex mechanisms of immune evasion.

--(BUSINESS WIRE)--BostonGene, a leading provider of AI-based molecular and immune profiling solutions ... and Director of the Multiparametric In Situ Imaging Laboratory at Weill Cornell Medicine ...

The cytokine interleukin-15 (IL-15) plays a crucial role in the immune system by affecting the ... ANKTIVA is a first-in-class IL-15 agonist IgG1 fusion complex, consisting of an IL-15 mutant ...

Credit: Shutterstock. "This combination of a TLR ligand and an anti-OX40 antibody can cure multiple types of cancer and prevent spontaneous genetically driven cancers," the authors write.

That is the basic idea behind material-driven in situ tissue engineered vascular grafts. Besides replacing tissue functionality upon implantation, these scaffolds should control the host's immune ...

To promote an immune response, the Morris Lab is looking at three techniques of in situ vaccination which occurs in the body and turns the tumor into an active site for the immune system, Onate said. ...

Cowpea mosaic virus, when injected into cancerous tumors, stimulates the immune system to attack and ... anti-tumor impact when used as an in situ vaccine to treat cancer. Commercial development ...

The approach is called in situ vaccination, and it can take many forms such as a virus or targeted radiation. What they all have in common is that they are delivered directly into a tumor to help the ...