IgE is transported to mucosal tissues by CD23 and is also synthesized by the resident B cells. Its concentration is maintained in the tissue by the number of mast cells that express FcεRI at high ...

By simulating allergic reactions in a controlled environment, the test provides functional insights into IgE-mediated allergies. In the Hoxb8 MAT, mast cells are exposed to serum samples from ...

The relationship between food allergies and chronic illness represents one of the most significant yet underappreciated ...

Expert Rev Clin Immunol. 2013;9(3):211-216. Atopic dermatitis is a chronic inflammatory skin disease that commonly begins in early infancy, runs a course of exacerbations and remissions and is ...

Researchers from Shenzhen University have evaluated the potential antiallergic effects of the histone acetyltransferase KAT6A inhibitor WM-1119 on IgE-mediated mast cell activation and allergic ...

WATERTOWN, Mass.--(BUSINESS WIRE)--Seismic Therapeutic, Inc., the machine learning immunology company, today announced the presentation of preclinical data for its immunoglobulin E (IgE) protease ...

An allergic inflammatory response is a sequential interaction between various inflammatory and structural cells through their chemical messengers, which together lead to symptoms of allergy.