The most abundant type of antibody in our intestine is immunoglobulin A (IgA) which, once released, recognizes, and binds specific gut bacteria. On average, about 35% of the gut bacteria are ...

IgA nephropathy (IgAN) is an autoimmune kidney disease driven by immune cells that express a protein called CD38 on their ...

Antibodies to erythrocytes or leukocytes could not be found, but a precipitating antibody reactive with IgA in donor and normal human serum was discovered in the patient's serum. This antibody ...

Saliva-based diagnostics have emerged as a transformative approach in medical testing, offering a non-invasive and efficient alternative to blood sampling. However, the complexity of saliva, which ...

Biogen has revealed encouraging phase 2 results with its anti-CD38 antibody felzartamab in rare kidney disease IgA nephropathy (IgAN), which it hopes could join a series of first-in-class ...

We read with great interest the study by Wunsch et al 1 published in this issue of Polish Archives of Internal Medicine, which validated the prognostic ability of 2 previously ide ...

There are five main types (isotypes) of antibodies, each with distinct structures and functions: IgG, IgM, IgA, IgE, and IgD. Illustration of the five major antibody (immunoglobulin) types ...

monoclonal antibody, in the territory outside of Greater China. Climb Bio believes CLYM116 is a potential best-in-class approach to address significant unmet need in patients with IgA nephropathy ...

Climb Bio Inc. has entered into an exclusive license agreement with Beijing Mabworks Biotech Co. Ltd. for rights to develop and commercialize MIL-116 (now CLYM-116), an anti-APRIL monoclonal antibody ...

Transcutaneous immunization, a topical vaccine application, combines the advantages of needle-free delivery while targeting the immunologically rich milieu of the skin. In animal studies, this ...

Serological testing in people who have IgA deficiency:- What is the sensitivity and specificity of IgG tissue transglutaminase (tTG), IgG endomysial antibodies (EMA) and IgG deamidated gliadin peptide ...