They are already working on a new differentiation protocol that converts the hPSC starting cells into cells from other organs so that further multi-tissue organoid models will be available for ...
Cross-section through part of a retinal organoid: On day 143 of their differentiation, the inner nuclear layer (bottom) contains the cell bodies of functionally distinct cells: those of the ...
Human induced pluripotent stem cell (iPSC)-derived retinal organoids are an emerging tool for the study of retinal development, disease modeling and drug discovery. In this webinar, we will focus on ...
The team noted high expression of RA synthesis genes early in human retinal organoid development that decreased over time, similar to what occurs in zebrafish. To test whether RA promoted M or L cones ...
The researchers found that the dissociated retinal organoid neurons retained the ability to form synaptic connections, based on the movement of the labeled virus from one cell to the next. “What was ...
Newcells provides a quick and accurate in vitro retinal drug toxicity testing service using intricate retinal organoid models created in-house or from client-supplied cells. The retinal toxicity ...
Image Credit: Newcells Biotech (B) Retinal organoid viability following transduction by AAV. ATP assay was assessed as an indicator of viability at 27 days post-transduction with AAV vectors.