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"When we tested phages that could not go dormant, the CRISPR system did not work nearly as well." After isolating the bacteria that survived, and letting the survivors repopulate the flask ...
Bacteria can fend off viral infections by chopping up their DNA with their CRISPR-based immune system ... bacterial immunity and facilitate infection by other viruses. “This work shows that phages can ...
So why do we call it CRISPR? Cas proteins are used by bacteria to destroy viral DNA. They add bits of viral DNA to their own genome to guide the Cas proteins, and the odd patterns of these bits of ...
(3) Scientists directly provide the sequence encoding all CRISPR components, a Cas protein and a guide RNA, into the target microbe. (4) Alternatively, scientists co-opt the bacteria’s endogenous ...