For example, as very short regions of homology are sufficient for the recombination, manipulating regions containing repetitive sequences can be problematic. As most recombineering-based methods ...

Multiple loss-of-function alterations in genes that are involved in DNA repair, including homologous recombination repair ... In cohort A, imaging-based progression-free survival was significantly ...

Those that occur within genes may result in pathogenic ... BRCA2, and homologous recombination deficiency. Only articles published in English were reviewed. The final reference list was generated ...

1998 Gene conversion tracts from double-strand break repair in mammalian cells in mammalian cells. Mol Cell Biol. 1998;18:93-101. Johnson RD, Liu N, Jasin M. 1999 Mammalian XRCC2 promotes the repair ...

EGFR Inhibitors Plus Bevacizumab are Superior Than EGFR Inhibitors Alone as First-Line Setting in Advanced NSCLC With EGFR Mutations and BIM Deletion Polymorphisms (BIM-CLICaP) Homologous ...