and premature coronary artery disease. Statins lower plasma cholesterol by upregulating LDL receptor gene expression and are consequently relatively ineffective in homozygous familial ...

BUFFALO, N.Y. — A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington’s disease?

Carrie Bryson, a 61-year-old Westminster resident, was diagnosed with Huntington’s disease in January of this year. Huntington’s disease is a fatal genetic disorder that causes the progressive ...

The study indicates that a possible treatment for Huntington's disease would be to encourage the brain to replace lost cells with new, functional ones and restore the brain's communication pathways.

A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington's disease? They found that ...

What can Gregor Mendel’s pea plants tell us about human disease ... who is most often a carrier (heterozygous) but who might be affected (homozygous). Males, on the other hand, have only ...