We have characterized four sequential enzymes that transform 1-hydroxy-N-methylcanadine to narcotoline hemiacetal, completing our elucidation of noscapine biosynthesis in opium poppy. Two ...

The total synthesis of a bisanthraquinone natural product provides the opportunity to investigate the medicinal properties of a new class of antibiotics.

These are cyclic, due to the ring-closing effect produced by chemical bond formation. Note that an attack on an aldehyde to produce a hemiacetal results in a 6-membered ring.