The research team discovered that artemisinin is activated by the iron contained in heme, a component of hemoglobin, rather than by free-floating iron. The source of heme is both the parasite’s ...

In all of these roles, heme is employed as the prosthetic group or cofactor of specific hemoproteins. Heme can be thought of as a 'domesticated' form of iron in which the uncontrollably reactive ...