Or, in another example, can isolated stem cells of non-hematopoietic origin reconstitute and rescue a lethally irradiated mouse? And do muscle fibers derived from lineage-heterologous stem cells ...

In the study "Long-term lineage commitment in hematopoietic stem cell gene therapy," published in Nature, the team investigated how stem cells used in gene therapy behave differently depending on ...

Then they mapped single-cell lineage output to gene expression against a cDNA library to generate a molecular bridge database. Lu and her team used the database to quantify HSC lineage outputs across ...

The positively selected cells were stained with phycoerythrin-conjugated lineage markers (PharMingen ... evidence for a relationship between normal hematopoietic colony-forming cells and cells ...

More information: Sarmistha Banerjee et al, YY1 knockout in pro-B cells impairs lineage commitment, enabling unusual ...