This study proposes a new mechanism by which Chd1 senses and responds to DNA unwrapping via EDBL engagement to suppress ...

Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA strands, thereby pulling apart the two strands. As the helicase moves along the DNA ...

Figure 1: Ribbon diagram representation of the structure of a, a member (Rep) of the Rep/PcrA family of helicases and b, a member (T7 gene 4 protein) of the hexameric helicase family. After having ...

Werner syndrome (WS) is a progeroid disorder caused by mutations in a protein containing both a DNA exonuclease and DNA helicase domains. Previous studies indicated that males lacking the helicase ...

The small molecule works by inhibiting ALC1 (chromodomain-helicase-DNA-binding protein 1-like), a chromatin remodeller and ...

RNA helicase, RNA, and single-stranded DNA to form a nuclear protein complex which may be involved in transcriptional events as a member of an mRNA factory. Discovery of a novel O-glycosylation of ...

This process of protein synthesis occurs in two stages ... This unwinding of the helix is caused by an enzyme (helicase enzyme). The enzyme RNA polymerase attaches to the DNA in a non-coding ...

Supinoxin blocks SCLC progression through the DDX5 protein. Researchers in Tran's ... DDX5 belongs to a family of RNA helicases, enzymes that unwind RNA molecules to begin a process allowing ...