Resistant individuals had in their cells two copies of a mutation that disrupted the entryway through which HIV viruses entered white blood cells. People who inherited just one copy of the change ...

A compound that blocks the CCR-5 protein might prevent HIV infection as if a person had naturally inherited the mutation. This discovery has not yet translated into new treatments. A dozen ...

However, the optimal means of interpreting these sequences is not known. HIV-SEQ identifies mutations and helps in their interpretation, but does not have the logical or heuristic power to provide ...

NNRTIs bind to a hydrophobic pocket near the catalytic site of HIV-1 RT and inactivate enzymatic activity. NNRTI-resistance mutations & their mechanism of drug resistance The most prevalent NNRTI ...