Biological cells often possess thin, hair-like protrusions on their surface known as cilia, which serve various functions ...

Scientists from Germany and Italy have uncovered details of the protective layer that surrounds the fine protrusions of cells ...

For years, scientists studying brain aging have focused on proteins and DNA. But what if a crucial piece of the puzzlehas ...

either through viral vectors or drugs that target the enzymes that form the glycocalyx, to restore BBB function during aging or neurological disease,” Kipnis and Smyth wrote.—Madolyn Bowman Rogers ...

Besides, the role of the brain endothelial glycocalyx in BBB function has been increasingly recognized. The glycocalyx coats BBB’s luminal surface and mediates many processes, including cell ...

restoring a more "youthful" glycocalyx, they improved the integrity of the blood-brain barrier, reduced neuroinflammation, and measurably improved cognitive function. "Modulating glycans has a maj ...

The researchers found that a deficit in mucin – a sugar-coated protein responsible for proper glycocalyx function – led to neuroinflammation in older mice. When mucin was reintroduced to the ...

When the team reintroduced those critical mucins in aged mice, restoring a more “youthful” glycocalyx, they improved the integrity of the blood-brain barrier, reduced neuroinflammation, and measurably ...