Panelists discuss how patients with immunoglobulin A (IgA) nephropathy typically present with microscopic or gross hematuria, often during upper respiratory infections, along with variable proteinuria ...

Edgar Lerma, MD, provides insights into the pathophysiology of IgA nephropathy (IgAN) and the therapeutic promise of ...

IgA nephropathy (IgAN) is characterized by the deposition of IgA1-containing immune complexes in the glomerular mesangium. The pathogenesis follows a 4-hit cascade: ...

Figure 1: Renal biopsy specimen showing focal necrotizing glomerulonephritis in a patient ... Moreover, the results cannot explain the pathogenesis of ANCA-associated vasculitides other than ...

UpToDate: “IgA nephropathy: Treatment and prognosis.” Mayo Clinic: “IgA Nephropathy (Berger’s disease).” JAMA Internal Medicine: “Evaluating a New International Risk-Prediction Tool in ...

IgA nephropathy is an autoimmune kidney disease, and complement, a component of the innate immune system, plays a role in the condition's pathogenesis. Investigators have developed and tested a ...

In a new study, a joint study by Tokyo University of Science and Juntendo University researchers has become the first to demonstrate the presence of IgA autoantibodies that bind to a specific ...

Table 1. Diabetic Nephropathy Stages: Cutoff Values of Urine Albumin for Diagnosis and Main Clinical Characteristics Stages Albuminuria cutoff values (ref. 14) Clinical characteristics (ref. no.) ...