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Comprehensive reference genomes have now been assembled for six ape species: siamang (a Southeast Asian gibbon), Sumatran ...
Alternatively, reads can also be aligned to a reference genome to identify small genetic variations (below right). Where de novo assembly can be thought of as assembling a puzzle without the use of ...
Scientists report adaptive divergence in cryptic color pattern is underlain by two distinct, complex chromosomal rearrangements, where millions of bases of DNA were flipped backwards and moved from ...
Reference genome assemblies provide a map of a species’ DNA sequence and its spatial context—that is, where along the chromosomes a specific piece of DNA sequence can be found. In the past ...
Understanding the material basis of adaptive evolution has been a central goal in biology dating back to at least the time of ...
Even with a near-perfect assembly, there are still limitations to a genome’s ability to serve as a reference for an entire species. Pangenome graph construction is currently a research frontier in ...
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