This approach can make it more efficient to align protein sequences and DNA for genome assembly, which is a fundamental problem in computational biology. Giulia Guidi, assistant professor of computer ...

Therefore, simply recasting our original problem into a slightly different framework converts genome assembly into a tractable computational problem. The time required to run a computer ...

Giulia Guidi, assistant professor of computer science in the Cornell Ann ... When sequencing a genome, biologists end up with thousands or millions of short DNA sequences that must be put together ...

Computer programs then take those segments and determine ... The old software would basically give up on these hard parts of the genome. That's the problem with genome assembly," Schatz said. "Our new ...

Computer software has to recognize the cases ... high-quality fragments raised the overall accuracy of the genome assembly to 99.88 percent, which shows that this works. But the researchers ...

More information: Kazuhiro Sato et al, Chromosome-scale genome assembly of the transformation-amenable common wheat cultivar 'Fielder', DNA Research (2021). DOI: 10.1093/dnares/dsab008 ...

Computer programs then take those segments ... That's the problem with genome assembly," Schatz said. "Our new program, using the latest sequencing data and the latest assembly algorithms, knows ...