The mechanism of action of bupropion is unknown, as is the case with other antidepressants. However, it is presumed that this action is mediated by noradrenergic and/or dopaminergic mechanisms.

Bupropion HCl 100mg, 150mg, 200mg; sust-rel tabs. Swallow whole. Avoid bedtime dosing. ≥18yrs: initially 150mg once daily in the AM for at least 3 days; if tolerated, increase to 150mg twice ...