CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Aconsortium of 17 laboratories worldwide has presented results contradicting a highly cited study that described a technique to create conditional knockout mice using CRISPR. The preprint, published ...

We performed genome editing of the embryos using the CRISPR-Cas9 system and electroporation to generate the Tle6 hetero ...

A minimum of 3 positive founders will be delivered. To produce CRISPR/cas9-mediated gene indels to generate knock-out mice or rats. The investigator will provide or purchase the CRISPR gRNA(s). TGEF ...

Adding to the list of issues that can occur with CRISPR, a team of researchers now reports a high frequency of unwanted duplications while engineering genetic insertions in mice. Worryingly to the ...

To create mice with two fathers, the researchers targeted 20 of these imprinted genes in male embryonic stem cells, using ...

CRISPR/Cas9 techniques are quickly growing in popularity for the generation of new mouse models for research. Though the approach is relatively simple, many researchers struggle with understanding the ...

Now, however, scientists have developed a series of sophisticated mouse models using CRISPR ('clustered regularly interspaced short palindromic repeats') technology that allows them to ...

Dry shipper rental $7 per day ($2,000 deposit for guaranteed return) $6.65 per day ($2,000 deposit for guaranteed return) $10.50 per day ($2,000 deposit for guaranteed return) Generation of transgenic ...

(REUTERS) British scientists are testing cutting edge gene editing techniques in mice, by inserting a jelly fish gene that makes their skin green. The research uses CRISPR-Cas9, a gene editing ...