In the present study, we propose the use of gene-modified mesenchymal stem cells (MSCs ... 9L glioma of intracranially implanted MSCs engineered to secrete the immunoregulatory cytokine IL ...

There are promising new results in animal models whereby mesenchymal stem cells (MSCs ... various applications of MSCs in cancer gene therapy.

Reasoning that stem cells’ stiffness-sensing properties could be used to deliver therapeutics in a targeted way, his team engineered human MSC genomes by placing a promoter, activated when the cells ...

What if we could reprogramme the TME itself? Cutting-edge research suggests that engineered mesenchymal stem cells (MSCs) could disrupt this shield – targeting tumours in a way that finally ...

1 Scientists are exploring substitutes for transplantation, including the use of human pluripotent stem cells ... state a cell is in. This work was recently published in Molecular Systems Biology. 3 A ...

Stromal cells – also known as mesenchymal stem cells (MSCs ... prostaglandin E2 (PGE2), tumor necrosis factor-inducible gene 6 protein (TSG6), CCL-2, and programmed death ligand 1 (PD ...

Research teams have created a versatile set of gene delivery systems that can reach different neural cell types in the human ...

In both cases, the engineered cells adopted unique gene expression profiles – highlighting ... because the microglia are derived from induced pluripotent stem cells, they could possibly be ...

He’s got new blood. A Long Island hospital said it administered life-changing Lyfgenia gene therapy treatment and successfully wiped away sickle cell disease from a Laurelton man. Cohen Children ...

Medical centers also have the capacity to handle only a limited number of gene therapy patients. Each person needs expert and intensive care. After a patient’s stem cells have been treated ...