Nature3y
GPCRs are membrane-bound proteins that have seven membrane-spanning domains connected by intracellular and extracellular domains.
G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research.
Nature4y
G-Protein-Coupled Receptors, Pancreatic Islets, and Diabetes
G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...
Fierce Biotech5d
Sotio takes up option on ADCs, while Boehringer inks GPCR discovery pact
Sotio Biotech is pushing deeper into bispecific antibody-drug conjugates (ADC), taking up its option to use Synaffix’s ...
Hosted on MSN1mon
New numbering system standardizes protein domain comparison for better research
Peter Hildebrand, professor of membrane and cell biophysics at Leipzig University, who led the international study, says, "Our new numbering system is an important step forward in GPCR research.
EurekAlert!2y
GPCR Family Receptors (IMAGE)
Key GPCR family receptors that are related to diseases. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or ...
EurekAlert!21d
New advances in targeted therapies for PIK3CA-mutated cancers
PI3K signaling pathways. Upon activation by RTK, GPCR, Integrin, and Ras, p110 loses inhibition by p85 and converts PIP2 to PIP3. PIP3 recruits AKT to the cell membrane, where AKT is activated ...