G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...

Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data science ...

GenAI offers a realistic path forward in tackling previously undruggable targets, with the potential to reshape the entire ...

April 23, 2025). Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data ...

"The key to understanding this family of proteins has been the determination of their molecular structure. "Now, half of all medications achieve their effect through G-protein-coupled receptors. It is ...

A new study in Engineering explores the role of astrocytic G protein-coupled receptors in drug addiction. It shows that these receptors, including ...

Structure Therapeutics Inc.’s GPCR share price has surged by 29.14%, which has investors questioning if this is right time to sell.

Cysteinyl leukotrienes (CysLTs) are potent bronchoconstrictors, playing pivotal roles in inflammatory diseases. These lipid mediators exert their effects by activating two G protein-coupled receptors, ...