G protein-coupled receptors (GPCRs) are expressed on the surface of cells ... be classified based on a combination of their structural and functional features—for example, how they bind to ligands. 5 ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

A number of cell surface and nuclear receptors mediate their actions via dimerization. While this has been well established, the dimerization of G-protein coupled receptors (GPCRs) (that ...

Seeking students to join a new and growing lab that seeks to understand the molecular causes of cancer in order to develop better therapies and improve patient outcomes. Our lab seeks to understand ...

Scientists have discovered how chemokines and G protein-coupled receptors selectively bind each other to control how cells move.

G protein-coupled receptors (GPCRs) are involved in many diseases, yet raising therapeutic antibodies against them is notoriously difficult because the transmembrane receptors contain only short ...

Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data science ...

Drugs that act on GPCRs, or G protein-coupled receptors, include more than 400 ... bacteria and compounds found in food," he said. "For example, we identified a couple of phytochemicals in corn ...

The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...

Adhesion G protein-coupled receptors (GPCRs ... bioinformatics and structural biology." For example, the newly developed ...

Drugs that act on GPCRs, or G protein-coupled receptors, include more than 400 ... bacteria and compounds found in food," he said. "For example, we identified a couple of phytochemicals in corn ...