G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

G-protein coupled receptors regulate hormone secretions in ... of each of these hormones depends on specific factors. For example, beta cells secrete insulin in response to increased blood glucose ...

A new study in Engineering explores the role of astrocytic G protein-coupled receptors in drug addiction. It shows that these receptors, including ...

Adhesion G protein-coupled receptors (GPCRs ... bioinformatics and structural biology." For example, the newly developed ...

The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...

A new study, published today in Nature Chemistry by researchers from the University of Pittsburgh and Yale University, shows ...

He will in particular discuss targets of interest and examples that will include G-protein coupled receptors (GPCRs) with an emphasis on allosteric modulators and ion channels.