G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

Researchers have revealed the mechanism underlying GPCR function using a GPS nuclear magnetic resonance (NMR) technique.

Recent breakthroughs in understanding the prostaglandin D2 (PGD2) receptor 1 (DP1) are paving the way for innovative ...

The subcellular signaling landscape of receptors. G protein-coupled receptors (GPCRs) form the largest receptor family in humans. GPCRs mediate the effects of diverse natural liga ...

Taste, pain, or response to stress—nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers at the University ...

In this randomized controlled trial, oveporexton use significantly improved symptoms of narcolepsy over eight weeks. 2.

On the 17 th of June 2025, Mr Kevin Assoumou will defend his PhD thesis entitled "Regulation of GPCR anterograde trafficking". His thesis was conducted under the direction of Pre Miriam Stoeber from ...

Recent breakthroughs in understanding the prostaglandin D2 (PGD2) receptor 1 (DP1) are paving the way for innovative anti-inflammatory and ...

MetaVia Inc. (Nasdaq: MTVA), a clinical-stage biotechnology company focused on transforming cardiometabolic diseases, today announced that an abstract highlighting pre-clinical data on DA-1241, a ...