G-protein coupled receptors regulate hormone secretions in ... Two major forms of diabetes exist, type 1 and type 2. Type 1 diabetes is characterized by a complete lack of insulin that leads ...

To help in the rational design of new compounds for treating hyponatremia and polycystic kidney disease, the authors solve cryo-EM structures of the G protein-coupled vasopressin type 2 receptor ...

New research reveals how chemokines and G protein-coupled receptors selectively bind each other to control how cells move.

G protein-coupled receptors (GPCRs) are involved in many diseases, yet raising therapeutic antibodies against them is notoriously difficult because the transmembrane receptors contain only short ...

The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...

A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role ...

They have identified a crucial protein, G protein-coupled receptor 107 (GPR107 ... the internalization of angiotensin II receptor type 1 (AT1R) in podocytes through clathrin-mediated endocytosis.

Scientists have discovered how chemokines and G protein-coupled receptors selectively ... showed that the scientists could change how T cells, a type of white blood cell, move, turning down ...