Espin induces abundant filopodia formation at the leading edge and along the sides, exerting force for cells migrating in ...

The lobate shape of lymphatic endothelial cells puzzled researchers—now they’ve found it helps stabilize lymphatic ...

Filopodia are specialized structures that extend from the cell membrane to allow a cell to explore the environment around it. These thin protrusions are full of a protein called actin, which, in ...

Tip cell filopodia express high-affinity tyrosine kinase receptors for VEGF, which dimerize and autophosphorylate upon ligand binding.

Computer simulations of filopodia dynamics indicate that a rotating actin structure inside the tube results in friction between the membrane and the actin, leading to the spiral form that is observed.