Most important for the survival of the hair follicle are the epithelial stem cells within the follicular bulge that communicate with the fibroblasts of the dermal papilla. These structures may be ...

Traditionally, fibroblasts—specialized supporting cells within the dermis—have been believed to play a key role in producing collagen. In humans, collagen is formed before and after birth.

During dermal development multipotent fibroblasts differentiate into distinct subpopulations that create the dermal sublayers, papillary, reticular and dermal white adipose tissue (DWAT). These ...

They discovered that keratinocytes, the surface cells of the skin, are responsible for producing collagen, which is then transferred deeper to form the dermis. Later, fibroblasts migrate into this ...