The American doctor has revealed that enigmatic DNA circles are present in more than half of patients with highly aggressive ...

the extrachromosomal DNA (ecDNA) found in some cancer cells is not always split evenly. Lacking centromeres, these circular bits of DNA are often unevenly parceled to daughter cells. Some daughter ...

“We see firsthand that even when two patients both have MYC on ecDNA, the structure of that circular DNA can ... that organoids bearing MYC on extrachromosomal DNA could shift their dependency ...

Small circles of extrachromosomal DNA appear to be widespread in mammals, and may be byproducts of small deletions in the nuclear DNA of somatic cells. A series of rodent experiments showed that even ...

It has been determined that prokaryotic DNA replication occurs at a rate of 1,000 nucleotides per second, and prokaryotic transcription occurs at a rate of about 40 nucleotides per second (Lewin ...

extrachromosomal DNA (ecDNA). The team found that some pancreatic cancer cells gain a major survival edge by carrying copies of critical cancer genes—such as MYC—on circular pieces of DNA that ...