During vascular development, coordinated control of endothelial cell behaviour at the levels of cell migration, proliferation, polarity, differentiation and cell–cell communication is critical ...

Photo Caption: A human melanoma cell exhibits a specific polarity which helps attaching to the endothelial layer of the blood vessel (ezrin stained in orange). After the word “cancer”, perhaps the ...

"This polarity seems to help the free cancer ... the manipulated cells were no longer able to attach efficiently to endothelial cells. With this discovery, the DKFZ researchers have not only ...

Due to the sudden rupture of the aortic wall, aortic dissection is a life-threatening condition that requires immediate ...

Injectable endothelial cell therapy may alter the landscape of corneal endothelial disease treatment. Vyznova cell therapy received regulatory approval from Japan’s Pharmaceuticals and Medical ...

The retrospective comparative analysis looked at the safety and efficacy of injectable human endothelial cell therapy in patients with corneal edema in clinical trials conducted in Japan and El ...

AURN001 is a combination cell therapy product candidate comprised of allogeneic human corneal endothelial cells (neltependocel) and a rho kinase inhibitor (Y-27632). This investigational product ...

Aurion will operate as a separate company with full support from Alcon to advance its clinical-stage allogeneic cell therapy asset, AURN001, into Phase 3 for corneal edema secondary to corneal ...