The bacteria that cause tuberculosis (TB) may have an "on-off switch" that lets them pause and restart growth, according to a ...

To fully understand how genome integrity is maintained, David Cortez, Ph.D., and colleagues have generated a "catalog" of the proteins present at sites of DNA duplication (replication forks ...

More information: Sophie L Williams et al, Replication‐induced DNA secondary structures drive fork uncoupling and breakage, The EMBO Journal (2023). DOI: 10.15252/embj.2023114334 ...

A protein called PriC allows DNA replication to proceed in Escherichia coli when the complex that usually initiates this process is compromised.

Furthermore, they also successfully improved the DNA to evolve to a DNA with a 10-fold increase in replication efficiency by continuing this DNA replication cycle for about 60 days. By adding the ...

During DNA replication, special enzymes move up along the DNA ladder, unzipping the molecule as it moves along. New nucleotides move in to each side of the unzipped ladder. The bases on these ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind ...

As previously mentioned, the location at which a DNA strand begins to unwind into two separate single strands is known as the origin of replication. As shown in Figure 1, when the double helix ...

The bacteria that cause tuberculosis (TB) may have an “on-off switch” that lets them pause and restart growth, according to a ...

Knowledge of the structure of DNA enabled ... of 1 mM about 10 6 times per second). The rapid rates of molecular movement were thought initially to allow a process like DNA replication to occur ...