University of Illinois at Urbana-Champaign researchers have developed a CRISPR-based diagnostic tool capable of detecting ...

a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms. The study, published in Nature Communications, was conducted by researchers from ...

The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell. After that, the next step in CRISPR gene editing is usually to alter that piece of DNA. However ...

2 The team next wanted to test these findings in a physiological context; they were curious to see how negative supercoiling, or under twisting of DNA that happens during normal transcription and ...

Early reports have demonstrated that CRISPR effectively excises integrated human immunodeficiency virus type 1 (HIV) from cells. 1,2 For Michele Lai from the University of Pisa, these studies raised ...