For the Liu Lab, necessity is truly the mother of invention. The researchers were examining how the 3D organization of the ...

In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA ...

Genes have to be expressed in the right place, at the time, and at the right levels. Scientists wanted to know more about how ...

Johns Hopkins scientists develop mRNA "booster" as potential new way to treat rare genetic diseases marked by too low levels ...

Findings show potential for new lipid-based delivery formulations as a platform technology for immunizationPhiladelphia, PA, ...

For natural cells, the so-called central dogma of molecular biology describes how protein synthesis occurs through ...

Radiation therapy is a powerful tool for fighting cancer, but it comes with painful side effects. About 60% of cancer ...

Assembling DNA nanostructures at more moderate temperatures opens up the possibility of using the structures in biomedical ...

Researchers have identified an ancient RNA-guided system that can target DNA, potentially expanding the genome-editing toolbox.

“Matthew really opened up a new form of epigenetic inheritance,” says Dr. Brent Derry, Eroglu’s supervisor. “He found that amyloids can be inherited, marking a significant discovery in protein-based ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive ...