Mount Sinai researchers have discovered distinct roles for two dopamine receptors located on nerve cells within the portion ...

A new pill, tavapadon, has shown potential in easing Parkinson’s symptoms while limiting side effects. In patients taking at ...

Mount Sinai researchers have discovered distinct roles for two dopamine receptors located on nerve cells within the portion ...

Study participants who had a higher ratio of D1-to-D2 brain dopamine receptors performed better on memory tasks during baseline testing compared to those who had a higher ratio of D2 receptors ...

Disruptions in the dynamic balance of D1-receptor mediated phosphorylation and dephosphorylation cascades in different regions of the neuron may lead to impaired integration of synaptic inputs.

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

Researchers have discovered distinct roles for two dopamine receptors located on nerve cells within the portion of the brain that controls approach vs. avoidance behavior.

In the study, Tavapadon, which works by mimicking dopamine and targeting the D1/D5 receptors, was found to have the same benefits as levodopa without the adverse effects, according to Hubert H.