Often characterized by involuntary motor or vocal tics, Tourette syndrome typically appears in childhood and affects up to ...

A new study in Engineering explores the role of astrocytic G protein-coupled receptors in drug addiction. It shows that these ...

Their findings, published in Nature Neuroscience, suggest that different aspects of reward-related behavior are supported by two distinct dopamine receptors, namely D3 and D1. "The previous ...

A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

The study specifically examines two types of GPCRs expressed on astrocytes: dopamine D1 receptors (D1R) and metabotropic glutamate receptor 5 (mGLUR5). These receptors respond to various ligands ...