Unlike the tongue, the skin does not perceive bitterness as a taste. However, keratinocytes—the skin's first line of defense—express bitter taste receptors that function as biological ...

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Illustration of bitter taste receptor function in keratinocytes. On the left, harmful substances enter skin cells, leading to cellular damage. On the right, bitter taste receptors located in the ...

These cells never come in contact with environmental signals like those near the skin but are studded with receptors that appear to get sensory input from hormones, proteins and other biochemical ...

Figure 1: A side-by-side comparison of the inflammatory process in a cutaneous setting. Several advantages are evident in the work of Thepen and colleagues 1. By targeting a receptor that is ...

This week (July 7), a team described its research on the olfactory responses of the skin. Hanns Hatt of Ruhr University Bochum in Germany and colleagues examined the response of epidermal cells known ...

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Citation: Bitter taste receptors in skin cells function as a defense mechanism against harmful substances, researcher discover (2025, February 25) retrieved 25 March 2025 from https://phys.org ...