Recombinant DNA, which is often shortened to rDNA ... several other papers followed building on the concept and adding techniques of construction and formation. In 1978, Werner Arber, Daniel ...

Among the cons are ethical concerns regarding the construction of rDNA molecules ... mutations that cause genetic diseases. Recombinant DNA can treat bleeding disorders, fight cancers, and ...

This 'recombinant DNA technology' was initiated soon after ... This approach dramatically simplifies the construction of large DNA molecules from constituent parts. Synthetic biologists are ...

It was the first drug produced through recombinant DNA technology and among the first genetically engineered products to be available to consumers. Following the success of Humulin, recombinant DNA ...

Virus-based transgene expression systems have become particularly valuable for recombinant protein production ... adapted to diverse crop species. The construction of a novel split-gene cassette ...

More information: Kazuhisa Uchida et al, Encapsulation of a Single-Stranded Form of DNA Impurities into the Capsid of a Recombinant Adeno-Associated Virus, Human Gene Therapy (2025). DOI: 10.1089 ...

The Purdue University Institutional Biosafety Committee (IBC) reviews research protocols involving the use of recombinant DNA (rDNA), synthetic nucleic acids, and/or biohazardous agents that present a ...

These Biosafety–Recombinant and Synthetic DNA policies and procedures exist to ensure that all research and activities involving the use of altered or synthetic and potentially hazardous DNA or RNA ...

In the context of the NIH Guidelines for Research Involving Recombinant DNA Molecules, recombinant DNA molecules are defined as either: molecules that are constructed outside living cells by joining ...

Recombinant DNA is one of the first stories in modern biotechnology history. The National Museum of American History contains collections which trace this foundational technique of genetic engineering ...

DNA impurities from plasmid and host cell DNA are encapsulated as single-stranded DNA within recombinant adeno-associated virus (rAAV) capsids. These impurities pose a quality control challenge in ...