In a significant step toward improving targeted cancer therapy, researchers from Japan have developed a novel nanocarrier ...

A crystal structure revealed an extraordinary double-helical assembly of the conjugate, with the helices arranged orthogonally to yield a highly porous architecture.

The structure reveals a helix protruding from the protein surface, which presumably interferes with the product DNA and thus promotes the dissociation of TDG from the DNA molecule.

The protein "MIPS" changes its internal structure when it becomes active. Its disordered active center becomes a defined structure with special functions. The protein plays a key role in the ...

Ubiquitin-like proteins (Ubls) are conjugated to target proteins or lipids to regulate their activity, stability, subcellular localization, or macromolecular interactions. Conjugation is achieved ...

DeepMind says its AlphaFold tool has successfully predicted the structure of nearly all proteins known to science. The AI lab is offering its database of over 200 million proteins to anyone for free.

ACROBiosystems has developed a series of specialized proteases for the screening and validation of ADC linkers, focusing on ...

The company has already used its protein-folding AI, AlphaFold, to generate structures for the human proteome, as well as yeast, fruit flies, mice, and more.

Google’s AI protein folder IDs structure where none seemingly existed Two intrinsically disordered proteins form a specific structure ID'ed by AlphaFold.

Scientists’ Work on Protein Structure, Which Governs All Aspects of Life, Wins Nobel Prize in Chemistry David Baker, Demis Hassabis and John M. Jumper revealed how amino acids shape protein ...

It took decades of painstaking research to map the structure of just 17 per cent of the proteins used within the human body, but less than a year for UK-based AI company DeepMind to raise that ...

From chaos to order: Proteins can re-structure themselves to create important substances Date: September 23, 2024 Source: Martin-Luther-Universität Halle-Wittenberg Summary: The protein 'MIPS ...