The story of the beta-lactamases is a case in point ... This is not true of all types of resistance, however. Resistance to oxazolidinones, such as linezolid in the case of S.

† VIMs are made up of 266 amino acid residues with the exception of VIM-7 (265 residues) and VIM-18 (262 residues). VIM-21, -22 and -27 have been assigned in the Lahey Clinic [201], but there ...

Ceftolozane with tazobactam (Zerbaxa, Merck Sharp & Dohme Limited) is a combination of a cephalosporin antibiotic, which predominantly covers Gram-negative bacteria, and a beta-lactamase inhibitor, ...

When looking deeper at the specific contribution from carbapenemase families, metallo-beta-lactamases (MBLs) were the most frequently identified carbapenem resistance mechanism. In the publication ...

mechanism and inhibition of both serine and metallo-beta-lactamases. I am interested in the molecular mechanisms by which resistance arises to a range of important antibiotic classes. I am also ...