Yet another critical cell cycle checkpoint takes place mid-mitosis. This check determines whether the chromosomes in the cell have properly attached to the spindle, or the network of microtubules ...

Prometaphase is an extremely dynamic part of the cell cycle. Microtubules rapidly assemble and disassemble as they grow out of the centrosomes, seeking out attachment sites at chromosome ...

Cancer researchers at Children's Medical Research Institute have discovered an "unexpected mechanism" that our cells use to ...

A mechanosensitive nuclear checkpoint triggers cell cycle arrest after chromosome mis-segregation. Chromosome segregation errors during mitosis, induced for example by centromere dysfunction (the red ...