The research team used specialized gene editing tools to identify and fix problems in the synthetic chromosome affecting how well the yeast could reproduce and grow under challenging conditions.

After more than a decade of work, researchers have reached a major milestone in their efforts to re-engineer life in the lab, putting together the final chromosome in a synthetic yeast (Saccharomyces ...

Final synthetic yeast chromosome unlocks new era in biotechnology. ScienceDaily . Retrieved February 12, 2025 from www.sciencedaily.com / releases / 2025 / 01 / 250122125522.htm ...

Researchers identified and corrected genetic errors that impacted yeast growth ... comprising 16 synthetic chromosomes and a new-to-nature tRNA neochromosome,” write the investigators.

Macquarie University researchers, alongside an international team, have achieved a significant milestone in synthetic biology by completing the final chromosome of the world's first synthetic yeast ...

The team heavily edited its synthetic chromosome, altering around one-sixth of its base pairs with additions, deletions, and replacements. Despite these changes, yeast cells that carried the designer ...

This study details the design and optimization of synXVI, a synthetic yeast chromosome, overcoming growth challenges through innovative genomic strategies.

“The synthetic yeast genome represents a quantum leap in our ability ... Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome. Nat Commun.

The research team used specialised gene editing tools to identify and fix problems in the synthetic chromosome affecting how well the yeast could reproduce and grow under challenging conditions.

(Nanowerk News) Macquarie University researchers have worked with an international team of scientists to achieve a major milestone in synthetic biology by completing the creation of the final ...