To Shakespeare’s Hamlet we humans are “the paragon of animals”. But recent advances in genetics are suggesting that humans ...

Translocation mutations can be unimportant to the person who has them. For example, a person may have a balanced translocation between chromosomes 7 and 21. The q arms of each chromosome have been ...

point mutations and chromosomal aberrations. In point mutations, one base pair is changed. The human genome, for example, contains over 3.1 billion bases of DNA, and each base must be faithfully ...

“There are treatments that are known to increase the frequency of chromosomal aberrations of different kinds, such as for example in vitro culturing of plant cells followed by whole plant regeneration ...

Originally created as a way to understand interactions between different mutations in proteins, the tool is now being used by McCandlish and his collaborators to learn about the complexities of gene ...

or is it driven by one or a few mutations that cause major changes in traits. Chromosomal rearrangements where large chunks of chromosomes are inverted, moved, deleted or duplicated, provide a ...

They identified previously unknown recurrent loss-of-function mutations that target genes regulating epigenetic pathways - ones that act on how tightly or loosely chromosomes are wound and thus ...

A team of biologists, environmental scientists and geneticists affiliated with multiple institutions across the U.S. has learned more about how mutations ... with two sets of chromosomes.

"Based on our data, we suggest that the cancer-associated mutations reported in POT1 affect the integrity of telomeres, leading to chromosomal abnormalities and in turn genomic instability ...

They identified previously unknown recurrent loss-of-function mutations that target genes regulating epigenetic pathways -- ones that act on how tightly or loosely chromosomes are wound and thus ...