However, the structure of chromatin also appears to serve a second, possibly more important role, in that it gives eukaryotic cells the capability to exert complex levels of control over gene ...

Chromatin state differences between cell types relate to cell-type-specific ... state (4 or 5), was within 125 kb of a TSS, excluding locations within 5 kb, and was associated with a gene ...

Proteins interact with DNA to regulate many vital processes in cells. Nearly 40 years ago ... To do so, they planned to stabilize proteins at their chromatin binding locations and use nucleic acid ...

Inside cells, DNA mixes with proteins to form chromatin within the nucleus. Within chromatin, structures called packing domains form when chromatin fibers fold together. These chromatin packing ...

Two views of an expanded skin cell nucleus from a person with progeria: On the left, antibody fluorescence imaging shows the ...

Both cell type and developmental stage can be deduced from measurements of chromatin accessibility in thousands of single cells, researchers at EMBL and the University of Washington show.

Cell behavior is influenced by chromatin architecture—the 3D shape of chromosomes—and which genes are accessible to proteins that promote regulatory T cell development. Studies involving ...

In a study published in Cell Reports, they and their colleagues show that the chromatin environment on DNA—the combination of DNA and histone proteins—plays a key role enforcing cell fate ...

Researchers have developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

But researchers at the University of Illinois at Chicago have discovered it is not protein, but chromatin, the portion of the cell nucleus that contains DNA, which provides this support.

Share on Pinterest Altering the structure of chromatin in cancer cells could help to kill them, say researchers. In the cell nucleus, DNA is wrapped around proteins called histones. Together they ...

Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, according to a study published in Advanced Science. Inside cells, DNA mixes ...