However, the structure of chromatin also appears to serve a second, possibly more important role, in that it gives eukaryotic cells the capability to exert complex levels of control over gene ...

Mapping a human cell gives researchers a view of subcellular architecture and sheds light on how cancer develops.

Chromatin state differences between cell types relate to cell-type-specific ... state (4 or 5), was within 125 kb of a TSS, excluding locations within 5 kb, and was associated with a gene ...

Inside cells, DNA mixes with proteins to form chromatin within the nucleus. Within chromatin, structures called packing domains form when chromatin fibers fold together. These chromatin packing ...

Proteins interact with DNA to regulate many vital processes in cells. Nearly 40 years ago ... To do so, they planned to stabilize proteins at their chromatin binding locations and use nucleic acid ...

Both cell type and developmental stage can be deduced from measurements of chromatin accessibility in thousands of single cells, researchers at EMBL and the University of Washington show.

In a study published in Cell Reports, they and their colleagues show that the chromatin environment on DNA—the combination of DNA and histone proteins—plays a key role enforcing cell fate ...

Cell behavior is influenced by chromatin architecture—the 3D shape of chromosomes—and which genes are accessible to proteins that promote regulatory T cell development. Studies involving ...

Researchers have developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

Share on Pinterest Altering the structure of chromatin in cancer cells could help to kill them, say researchers. In the cell nucleus, DNA is wrapped around proteins called histones. Together they ...

Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, according to a study published in Advanced Science. Inside cells, DNA mixes ...