Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct ...

However, the structure of chromatin also appears to serve a second, possibly more important role, in that it gives eukaryotic cells the capability to exert complex levels of control over gene ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, according to a study published in Advanced Science. Inside cells, DNA mixes ...

A novel technique to visualize gene-active and gene-repressive DNA regions in living cells, developed by a ...

Proteins interact with DNA to regulate many vital processes in cells. Nearly 40 years ago ... To do so, they planned to stabilize proteins at their chromatin binding locations and use nucleic acid ...

Wenzhou Medical University and collaborating institutions have identified a population of human neural retinal stem-like ...

How the cell achieves this feat remains largely unknown. Now, for the first time, EMBL scientists have directly observed this process in high resolution under the microscope using a new chromatin ...

Dr. Toshio “Toshi” Tsukiyama studies how cells regulate chromatin, the packaging proteins responsible for compressing several feet of DNA inside each cell’s tiny nucleus. This genetic material needs ...

and also interacts with DNA and histones as a pioneer factor that opens chromatin during development. We prepared ChIP DNA, as previously described 1, from HepG2 cells using a commercially ...

The work was published today in Cell Research. Chromatin comprises sections of DNA wrapped around proteins called histones to form nucleosomes collectively. One chromatin remodeling mechanism ...